She was born on 21 December, 1984 in Karachi, Pakistan.
She has received her primary education from Foundation Public School, Karachi and went to California for higher education at the age of 17, where she studied at the University of Southern California, but did not complete her degree.

Mahira also did a part time job as a Waitress in a restaurant while studying in US. During her studies in United States, Khan was a cashier at a Rite Aid store in Los Angeles.
Mahira Khan began her career as a VJ. Most Wanted on MTV Pakistan, and she then hosted Weekends with Mahira on Aag TV. In 2011, Khan made her film debut with Bol movie.
Mahira Khan, who has owned the remark of Pakistani people and also in other countries, is a true beauty. It is quite explainable how the people of Pakistan have a soft corner for her. She is the beauty.